Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in rats.
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چکیده
منابع مشابه
Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in rats.
Free radicals have been shown to play an important role in ischemia-reperfusion injury in several organ systems; however, the role of free radicals in central nervous system ischemia has been less well studied. Many potential free radical-generating systems exist. The primary products of these reactions, superoxide and hydrogen peroxide, may combine to produce hydroxyl radicals. Of the many pot...
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A differential outcome results from rapid middle cerebral artery (MCA) occlusion in young normotensive Wistar (NW) rats as compared to the spontaneously hypertensive stroke-prone (SHRSP) rat. The SHRSP invariably infarcts; the NW usually does not. To determine if segregation at a single autosomal locus explains the difference between strains, a NW male was crossed with several SHRSP females to ...
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ژورنال
عنوان ژورنال: Stroke
سال: 1989
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.20.4.488